Hmmm - your space group imposes a too fold screw acid parallel to the Y axis? If your dimer 2-fold is also parallel to the Y axis you should see a strong non crystallographic translation vector? Is that correct? Such things can complicate density. Eleanor
On Mon, 20 Apr 2020 at 20:24, Kyle Gregory < 00003632e92fcc15-dmarc-requ...@jiscmail.ac.uk> wrote: > Hello all, > > I have a homodimer structure in P1 21 1 spacegroup, the dimer is likely a > crystallographic artefact, where it looks like the monomer is rotated by ~ > 180 degrees around the Y axis. > > I am assessing ligand binding and each of the monomers display density at > the site but it is not as clear as I would like. A polder map does help > things but I was wondering if it is feasible, or if there are any tools, > that can be used to improve density based of the fact there are two > molecles present. Is there some way to sum (probably the wrong word here) > the densities at the binding site? > > Kind regards, > > Kyle > > ------------------------------ > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 > ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
