Hi

The Magnus Wolf-Watz lab in Umeå, Sweden has two openings in structural biology:

One PhD position directed at human protein kinases and their linkage to human 
cancer application deadline May 20

One Postdoc in structural biology of silk and cellulose modifying enzymes, 
application deadline April 15!

See below and www.biostruct.umu.se for more information

PhD position in biochemistry; structural biology of cancer linked protein 
kinases

A PhD position in biochemistry is available in the laboratory of Professor 
Magnus Wolf-Watz at the Department of Chemistry, Umeå University, Sweden. The 
PhD project is aimed at uncovering novel molecular mechanisms underlying the 
function of human protein kinases. Focus will be on two specific protein 
kinases that are intimately linked to a number of disorders in humans including 
various forms of cancer. The doctoral student will enter a multidisciplinary 
project that is built on collaborations with both Professor Kwangho Nam at 
University of Texas Arlington and with Marené Landström (Professor in pathology 
at Umeå University). The doctoral student will be trained in structural 
biology, protein production, biochemistry and biophysics and will collaborate 
with both cell biologists and computational chemists. Structural biology may go 
in any of the directions; single particle cryo EM, x-ray crystallography or 
protein NMR spectroscopy depending on the development of the research project 
and also depending on the interests of the doctoral student. The position is in 
part funded by the National Institute of Health (NIH).
2-year postdoc fellowship: Green Structural Biology in cellulose and silk 
biotechnology
An important aspect of green chemistry and a sustainable and circular economy 
is to develop environmentally friendly methodology to retrieve valuable 
chemicals from complex biomaterials. This interdisciplinary project tackles 
this challenging task by exploring the molecular mechanisms underlying 
enzymatic processing of recalcitrant natural polymers: cellulose and silk 
fibers. In the project we focus on two enzymes that bring novel functionality 
in cellulose and silk bio-processing by softening their structure and paving 
the way for further biocatalytic transformation of the fibers.
We are seeking a structural biologist with a strong background in biochemistry 
and/or protein production with different expression organisms. The structural 
biology background may be in any of the areas of NMR spectroscopy, single 
particle cryo EM or x-ray crystallography.   The successful candidate will have 
the possibility to define and shape the project dependent on background and 
ambitions and may focus on both enzymes and/or the structures of cellulose and 
silk-based biomaterials.


Please contact Magnus W-W for further information and guide to the application,


---------------------------------------------------------------------------------------------------------------------------
Dr. Magnus Wolf-Watz
Professor
Umeå University
Chemistry Department
Integrated Structural Biology (ISB), Twitter @ISB_UmU
Phone:+46 90 786 76 90
Lab Home Page: 
www.biostruct.umu.se/principal-investigators/magnus-wolf-watz/<http://www.biostruct.umu.se/principal-investigators/magnus-wolf-watz/>
Twitter: @watz_wolf



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