Hi,

Thanks. Several suggestions have been made:
1. UCSF Chimera can plot %ID and %Similarity
2. Consurf can plot conservation scores
3. AL2CO can also plot conservation scores

I have a protein with a fast molecular clock, so I need to think about this a 
bit more. 

Best wishes,
Reza

Reza Khayat, PhD
Assistant Professor
City College of New York
Department of Chemistry
New York, NY 10031

________________________________________
From: Clarke, Oliver <oc2...@cumc.columbia.edu>
Sent: Saturday, March 16, 2019 8:36 PM
To: Reza Khayat
Subject: [EXTERNAL] Re: CCP4BB Digest - 15 Mar 2019 to 16 Mar 2019 (#2019-81)

Hi Reza

You can do more or less this using the ConSurf server - or just load up your 
sequence alignment in Chimera, then you can assign %Id or similarity as a per 
residue attribute.

Cheers
Oli

> On Mar 16, 2019, at 8:03 PM, CCP4BB automatic digest system 
> <lists...@jiscmail.ac.uk> wrote:
>
> There is 1 message totaling 85 lines in this issue.
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> Topics of the day:
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>  1. Sequence variability mapped on a PDB
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> Date:    Sat, 16 Mar 2019 23:42:18 +0000
> From:    Reza Khayat <rkha...@ccny.cuny.edu>
> Subject: Sequence variability mapped on a PDB
>
> ?Hi,
>
>
> Can someone direct me to a program that can replace the B-factors of a PDB 
> with sequence variability calculated from a sequence alignment? I'm have 
> tried the PVS server, but my sequence alignment is too large for its liking. 
> Thanks.
>
>
> Best wishes,
> Reza
>
>
> Reza Khayat, PhD
> Assistant Professor
> City College of New York
> Department of Chemistry
> New York, NY 10031
>
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> End of CCP4BB Digest - 15 Mar 2019 to 16 Mar 2019 (#2019-81)
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