Hi, This paper:- doi:10.1107/S0907444903004219 <http://dx.doi.org/10.1107/S0907444903004219> I think will be of interest. Whilst 4 Angstrom resolution is not covered the article will indicate the tests you could make to evaluate your 'possible water like densities'. Best wishes, John
On Mon, Apr 13, 2015 at 7:14 PM, Sudipta Bhattacharyya < sudiptabhattacharyya.iit...@gmail.com> wrote: > Dear community, > > Recently we have been able to solve a crystal structure of a DNA/protein > complex at 4A resolution. After almost the final cycles of model building > and refinement (with R/Rfree of ~ 22/27) we could see some small water like > densities...all throughout the complex. Now my query is, whether one should > pick water molecules at this low resolutions or it is totally unscientific > to do so? > > Many thanks in advance...!!! > > My best regards, > Sudipta. > -- Professor John R Helliwell DSc
