Dear all I have a dimer that is related to each other by a crystallographic symmetry. My questions are:
a. how reliable are the delta G values given by PISA? Has there been an experimental study? b. For a dissociation delta G of say, around 30 kcal/mol, is it possible to estimate the sort of chemical forces (pH or ionic strength) that will be needed to experimentally produce the monomer? Thanks. Mohamed