PDRA Structural Biology of Membrane and Soluble Proteins and their complexes Salary: £ 31644 pa plus pension
You will join the Molecular Biophysics Group (www.biophysics.liv.ac.uk<http://www.biophysics.liv.ac.uk>) to work on a BBSRC-supported project on structure-function-mechanism studies of Cu-nitrite reductase and membrane bound nitric oxide reductase and the role of metabolon complex formation in controlling levels of cytotoxic NO. The project will link crystallographic studies with techniques to probe factors that control delivery of electrons and protons to the active site of these enzymes. You will be responsible for using established molecular biology procedures underpinning the overexpression and purification of a number of enzymes and their mutants including membrane proteins and undertake crystallographic, spectroscopic and mechanistic aspects of the programme. You will spend two periods of up to 4 weeks in the RIKEN laboratories in Japan as part of a collaborative programme alongside two PhD students working on membrane-bound nitric oxide reductases. You should have a PhD in a relevant area preferably with experience in protein crystallography and practical knowledge of molecular biology and membrane protein purification. The post is available for up to 4 years but the initial appointment will be made for 3 years. Excellent verbal and written communication skills are required. ------------------------------------- Informal enquiries to Professor S Hasnain, Max Perutz Professor of Molecular Biophysics on 0151 795 5149, email: s.s.hasn...@liv.ac.uk<mailto:s.s.hasn...@liv.ac.uk> or Dr S Antonyuk ------------------------------------------------------------ Dr. Svetlana Antonyuk Institute of Integrative Biology University of Liverpool Biosciences Building Liverpool L69 7ZB -------------------------------------- Phone: +44(0)151-795 0349 Email: s.anton...@liverpool.ac.uk<mailto:s.anton...@liverpool.ac.uk>
