Dear CCP4bb, We recently published a paper on collecting high resolution cryo-EM data of submicron (± 100 nm) 3D lysozyme crystals.(doi:10.1107/S0907444913002734 <http://dx.doi.org/10.1107/S0907444913002734> ). We are working hard to develop tools that can be used to interpret this data. In the mean time we would like to see if we can collect similar data of sub micron 3D protein crystals of more interesting proteins like membrane proteins or protein complexes. If there is anyone with very small, poorly diffracting crystal on the shelf please let us know. We can have a look at them with EM and even see mosaicity or stacking faults.
Kind regards, Igor Nederlof and Jan Pieter Abrahams
