Or, seeing that this is the CCP4BB <smile>, you could use the Xia2 pipeline 
from CCP4i - which will also use XDS if installed on your system.

> My recommendation would be to process with XDS. By using the autoProc 
> procedure from Global Phasing this is very easy, even for people who are 
> normally not able to run a program without a GUI. You will then have to run 
> XSCALE manually, which is again trivial once XDS had run correctly.
> 
> Good luck!
> Herman


Tony.


On 21 Mar 2013, at 07:41, <herman.schreu...@sanofi.com>
 wrote:

> Dear Kyriacos,
> 
> 
> 
> 
> -----Original Message-----
> From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of 
> Kyriacos Petratos
> Sent: Wednesday, March 20, 2013 6:25 PM
> To: CCP4BB@JISCMAIL.AC.UK
> Subject: [ccp4bb] Scaling with SCALA high and low resolution data sets
> 
> Dear All,
> 
> we have two data sets at about 0.9 and 1.9 Ang. resolution collected from a 
> single crystal.
> Integration with iMosflm seems to be fine like the scaling within each of the 
> data sets.
> When we try to merge and scale both of them with 'Scala' we get extremely 
> high scale factors for the lower resolution images varying between 
> approximately 30 and 200!
> Do we need to pay attention to some particular options for running the 
> program(s)?
> Thank you,
> 
> Kyriacos
> e-mail: petra...@imbb.forth.gr

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