Hi Ed,

     You can have both types of error in a single experiment, however you 
cannot determine 
statistical (precision or as Ian says uncontrollable) error with one 
experiment. The manufacturer
will usually give some specs on the pipette, 6ul +/- 1ul. In order to verify 
the specs
you would need to perform many pipetting experiments. But even if the 
manufacturer does not give 
any specs you still know that the pipette is not perfect and there will be a 
statistical error, you
just do not know what it is.


    In theory, accuracy or bias could be determined with one experiment. Lets 
say you thought
you had a 6ul pipette but actually it was a 12ul pipette. If you then compare 
the 'new' pipette
against a standard you could tell if it was inaccurate. Of course normally you 
would repeat 
this experiment as well because of statistical error. If detected bias can be 
removed. Systematic 
error may not be so easily detected. What if the standard is also biased.


Adam




> One can say it's inaccuracy when it is not estimated and imprecision
> when it is.  Or one can accept Ian's suggestion and notice that there is
> no fundamental difference between things you can control and things you
> can potentially control.

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