-----BEGIN PGP SIGNED MESSAGE----- Hash: SHA1 Dear Kavya,
As far as I understand the PDBRedo project attempts to make the reflections unbiased from the structure by a random shift of coordinates (e.g. 'NOISE' keyword in pdbset, although I am not aware of an investigation about whether this actually does make remove bias. It is safest to keep the same Rfree-set. Regards, Tim On 02/28/2013 06:54 AM, Kavyashree Manjunath wrote: > Dear users, > > Is it mandatory to use the same reflections for Rfree calculations > of a ligand bound data as that of its native? > > Thank you With Regards Kavya > > - -- - -- Dr Tim Gruene Institut fuer anorganische Chemie Tammannstr. 4 D-37077 Goettingen GPG Key ID = A46BEE1A -----BEGIN PGP SIGNATURE----- Version: GnuPG v1.4.12 (GNU/Linux) Comment: Using GnuPG with Mozilla - http://enigmail.mozdev.org/ iD8DBQFRLyQ2UxlJ7aRr7hoRAsHBAJ43K7f2lcSZwm6fD1pH8+grvrOqRACg1bdi PUUKJaUv8C4JgmcPNM6H9+U= =J47i -----END PGP SIGNATURE-----
