On 10/19/2012 10:37 PM, Acoot Brett wrote:
Will you please explain to me why the protein salt bridge can still
exist in the high salt concentration as used in the crystallization
condition?
You are saying it as if there is some fundamental law of nature that
says that salt bridges cannot be maintained at high salt concentration.
I know of no such law. The observation simply means that (mostly for
entropic reasons) the free energy of the salt bridge is still lower. If
you present your case as to why the salt bridges must be disrupted, we
can poke holes in it :)
Cheers,
Ed
--
Oh, suddenly throwing a giraffe into a volcano to make water is crazy?
Julian, King of Lemurs
