I have a buried active site and would like to determine if there is room for a water molecule in various mutants. Does anyone know of a good program to calculate this? I have heard of GRID and VOID but have never used them.
Thanks. -- Yarrow Madrona Graduate Student Molecular Biology and Biochemistry Dept. University of California, Irvine Natural Sciences I, Rm 2403 Irvine, CA 92697
