Dear Colleagues,
Please pass this ad on to any interested candidates.
Thanks and best wishes,
John
--
John Rubinstein
Molecular Structure and Function Program
The Hospital for Sick Children
555 University Avenue, Rm. 3330
Toronto, ON
Canada
M5G 1X8
Tel: (+001) 416-813-7255
Fax: (+001) 416-813-5022
www.sickkids.ca/research/rubinstein
*
Project and laboratory:*
A Postdoctoral position is available for the structural analysis of
protein complexes by electron cryomicroscopy (cryo-EM). Projects relate
to the analysis of protein complexes involved in endocytosis and
vacuolar sorting and/or bacterial and viral proteins that interact with
eukaryotic V-type ATPases. Candidates interested in studying other
protein complexes, particularly membrane protein complexes, are also
encouraged to apply. Applicants should have a PhD in biochemistry,
biophysics, biological chemistry, or a related discipline. A background
in structural biology is helpful but is not absolutely required. Please
send applications, including a complete CV and contact information for
three referees to: john.rubinst...@utoronto.ca
The Rubinstein group is a small and interactive group comprised of
members with diverse scientific backgrounds. We combine in-depth study
of systems of biological and biomedical interest with expertise in
cryo-EM technology and research into cryo-EM method development. By
maintaining strong connections between biology and methodology, we
ensure that our biological results are of the highest-possible quality
and our methodological developments are useful for 'real world'
problems. For more information, please visit
www.sickkids.ca/research/rubinstein
*The research environment and city of Toronto:*
Located in the heart downtown Toronto, The Hospital for Sick Children's
Research Institute includes approximately 225 Principal Investigators,
1,140 graduate students and postdoctoral fellows, and 800 other
scientific staff. Research in the Institute spans from basic biology to
clinical practices with seven research programs including Molecular
Structure and Function, Cell Biology, Genetics and Genome Biology, and
Developmental and Stem Cell Biology. The Research Institute is
affiliated with the University of Toronto, which is ranked 1st in Canada
and 19th worldwide in the Times Higher Education World University
Rankings (9th worldwide out of public universities). Toronto is
Canada's largest city and North America's 5th largest city. It is one
of the world's most multicultural cities with vibrant arts and culture
communities. Despite its size, it is also one of North America's safest
cities and is ranked as the 4th most liveable city in the world by The
Economist Intelligence Unit's Global Liveability Report.
*Selected Recent publications:*
Benlekbir, S., Bueler, S. A., Rubinstein, J. L. (2012). Structure of
the vacuolar-type ATPase from Saccharomyces cerevisiae. Nature
Structural and Molecular Biology, In Press.
Baker, L. A., Watt, I. N., Runswick, M. J., Walker, J. E., Rubinstein,
J. L. (2012). The arrangement of subunits in intact mammalian
mitochondrial ATP synthase determined by cryo-EM. Proceedings of the
National Academy of Sciences (USA) 109, 11675-80. (chosen by Faculty of
1000: f1000.com)
Lau, W. C. Y., and Rubinstein, J. L. (2012). Sub-nanometer resolution
structure of the intact T. thermophilus H+-driven ATP synthase. Nature
481, 215-8. (chosen by Faculty of 1000: f1000.com)
Lau, W. C. Y., and Rubinstein, J. L. (2010). Structure of intact
Thermus thermophilus V-ATPase by cryo-EM reveals organization of the
membrane-bound Vo motor. Proceedings of the National Academy of
Sciences (USA) 107, 1367-72. (chosen by Faculty of 1000: f1000.com)
