Donghui, There is detergent screen from Hampton: http://hamptonresearch.com/product_detail.aspx?cid=1&sid=39&pid=31
We set up detergent screen for crystal conditions we'd like to improve: 200nl(buffer) + 200nl(protein) + 40nl(detergent). Occasionally (very occasionally) it works, but don't put to much hope on it. Vitali On Thu, Jun 14, 2012 at 9:35 PM, wu donghui <wdh0...@gmail.com> wrote: > Dear all, > > I wonder if anyone has successful experience on using detergent to > crystallize non-membrane protein. Based on what criteria to choose > detergent to help solubilize and crystallize your non-membrane protein. > Thanks for any input or comments. > > Best regards, > > Donghui >