No they were not useless! I used them (probably better now with cryo data though)
Phil On 6 Jun 2012, at 16:02, Dyda wrote: >> I suspect that pure MIR (without anomalous) was always a fiction. I doubt >> that anyone has ever used it. Heavy atoms always give >> an anomalous signal > >> Phil > > I suspect that there was a time when the anomalous signal in data sets was > fictional. > Before the invent of flash freezing, systematic errors due to decay and the > need > of scaling together many derivative data sets collected on multiple crystals > could render > weak anomalous signal useless. Therefore MIR was needed. Also, current > hardware/software > produces much better reduced data, so weak signals can become useful. > > Fred > > [32m******************************************************************************* > Fred Dyda, Ph.D. Phone:301-402-4496 > Laboratory of Molecular Biology Fax: 301-496-0201 > DHHS/NIH/NIDDK e-mail:fred.d...@nih.gov > Bldg. 5. Room 303 > Bethesda, MD 20892-0560 URGENT message e-mail: 2022476...@mms.att.net > Google maps coords: 39.000597, -77.102102 > http://www2.niddk.nih.gov/NIDDKLabs/IntramuralFaculty/DydaFred > *******************************************************************************[m
