Dear Tim,

Thanks, The Jalview, output to textbox in PIR worked thr trick.

S.Jayashankar
Research Student
Institute for Biophysical Chemistry
Hannover Medical School
Germany.


On Tue, Mar 27, 2012 at 3:52 PM, Tim Gruene <[email protected]> wrote:

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> Dear Jayashankar,
>
> sorry, you did explain this in your model and I flipped clustalo with
> clustalw. Even though when I used the option '-convert', clustalw does
> not re-align the input but simply converts it, so in case it can read
> the clustalo output, this should do the job, shouldn't it?
>
> Have you tried reading the output file with clustalx or seaview or
> jalview? These programs should be able convert to various file formats
> without messing up with the alignment.
>
> Cheers,
> Tim
>
> On 03/27/12 15:44, Jayashankar wrote:
> > Dear Tim,
> >
> > I try to model a full length protein based on various domains solved
> > already.
> > In that case, alignment of multiple sequence should approximately locate
> to
> > the corresponding domain region.
> >
> > Clustalw results in an unexpected alignment file.
> > Whereas the output from clustal omega is perfect and the format what I
> need
> > is not given in the output option.
> >
> > Because I will be needing this .pir output file to model my target
> sequence
> > using modeller.
> >
> > thanks
> >
> > S.Jayashankar
> > Research Student
> > Institute for Biophysical Chemistry
> > Hannover Medical School
> > Germany.
> >
> >
> > On Tue, Mar 27, 2012 at 3:26 PM, Tim Gruene <[email protected]>
> wrote:
> >
> > Dear S. Jayashankar,
> >
> > have you tried the clustalw options '-convert -output=PIR'? This should
> > result in a pir-formatted output file.
> >
> > Tim
> >
> > On 03/27/12 10:18, Jayashankar wrote:
> >>>> Dear All,
> >>>>
> >>>> A bit offtopic question,
> >>>>
> >>>> Does any body know how can I get the PIR output of the aligned
> sequence
> >>>> from clustal omega.
> >>>> I have a full length protein solved, to give weightage during
> comparitive
> >>>> modelling, I use domains of the same/similar protein solved before.
> >>>> I expect an alignment something that looks like one below, and
> clustalw
> >>>> does'nt seems to work , but clustal omega does it. But there is no
> .pir
> >>>> format output.
> >>>>
> >>>>
> >>>> 1.cccccccccccccaaaaaaaaaabbbbbbbb
> >>>> 2.-------------------------------------bbbbbbbb
> >>>> 3.ccccccccccccc------------------------------
> >>>> 4.------------------aaaaaaaaaaa--------------
> >>>>
> >>>>
> >>>> Thanks
> >>>> S.Jayashankar
> >>>> Research Student
> >>>> Institute for Biophysical Chemistry
> >>>> Hannover Medical School
> >>>> Germany.
> >>>>
> >
> >>
>
> - --
> - --
> Dr Tim Gruene
> Institut fuer anorganische Chemie
> Tammannstr. 4
> D-37077 Goettingen
>
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