Dear members of the CCP4 community, 
I would like to attract your attention to the following opportunity.
Best regards
Adnane Achour


Karolinska Institutet

has a vacancy for

A doctoral student with doctoral grant in Molecular Immunology with a focus on 
NK cell modulation

Department
Department of Medicine, Huddinge

Description of research group and project
The Center for Infectious Medicine (CIM), Department of Medicine, Huddinge is 
looking for a PhD student who will work with Associate Professor Adnane Achour 
and his colleagues in order to establish the molecular mechanisms underlying 
the modulation of Natural Killer (NK) cells. The Achour research group is a 
part of the Center for Infectious Medicine (CIM), Department of Medicine 
Huddinge, and is localized within the Department of Microbiology, Tumor and 
Cell biology (MTC) at Solna campus. The research projects of the Achour group 
are bridging immunology and structural biology. Besides X-ray crystallography, 
techniques and approaches included within the proposed projects include 
molecular biology, functional immunology, biochemistry and biophysical 
approaches such as surface plasmon resonance. The overall aim of the projects 
is to assess the molecular basis for recognition of MHC class I   molecules in 
complex with different peptides by NK cell receptors and their effects on the 
modulation of NK cell responses.

Duties and responsibilities
The proposed projects represent a unique opportunity for a PhD student to 
acquire deep insights into immunology, biochemistry and structural biology 
using a variety of techniques already well established within the Achour 
laboratory and the laboratories of the two co-supervisors Prof. Klas Kärre 
(MTC, KI) and Prof. Per-Åke Nygren (Royal Institute of Technology, KTH). The 
duties/tasks and responsibilities of the PhD candidate are to lead the proposed 
project(s) under the supervision of his/her supervisors, and in close 
collaboration with his/her colleagues within the research group. By the end of 
the PhD study period, the candidate should have acquired a deep knowledge in 
immunology and biochemistry as well as a broad knowledge in structural biology. 
The PhD candidate should demonstrate excellent ability to design, perform, 
interpret, critically assess and contextualize generated data from experimental 
work. Furthermore, he/she should demonstrate aptitude to discuss and spread 
research results to both the national and international scientific community as 
well as to the non-scientific community.

Eligibility/Qualifications
The eligible candidate must hold a Master´s degree in immunology, biophysics, 
mathematics, biomedicine, virology, cell biology or equivalent. Previous 
experience in molecular biology and/or biochemistry is desirable but not 
absolutely required. We are seeking a highly motivated, creative person with 
good technical skills. The successful applicant should be fluent in English, 
with excellent communication capacity combined with the ability to interact 
effectively and work productively in a team. Emphasis will be placed on 
personal suitability as well as genuine enthusiasm for the topic.

To be eligible, an applicant must 
1. hold a Master’s (second-cycle) degree 
2. have completed course requirements of at least 240 HECs, of which at least 
60 at second-cycle level, or 
3. have otherwise acquired essentially equivalent competence in Sweden or 
abroad. 

Those who meet the requirements for general eligibility before July 1st, 2007, 
i.e. had completed a program of higher education for at least 180 HEC or the 
equivalent, will continue to do so until the end of July, 2015. 

Selection of qualified applicants is made on the grounds of their ability to 
benefit from doctoral (third-cycle) education. Karolinska Institutet applies 
the following assessment criteria: 
- Documented subject knowledge of significance to the research project
- Analytical skills confirmed by a scientific dissertation or the equivalent
- Other documented knowledge/experience of potential significance to doctoral 
(third-cycle) education in the subject 
An overall assessment of the applicants’ qualifications will be made. 

The vacancy will be filled on condition that the successful applicant is 
admitted to doctoral (third-cycle) education.

For further information on doctoral (third-cycle) education at Karolinska 
Institutet, see www.ki.se/doctoral.

Contact person: Ass. Prof. Adnane Achour, phone: 08-524 86216, 076-8090567, 
adnane.ach...@ki.se 

Union representatives: SACO: Ingrid Dahlman, ingrid.dahlman@ki., OFR: Eva 
Sjölin, eva.sjo...@ki.se

Form of employment:
Doctoral student

Notes
A doctoral student with doctoral grant years 1, and 2.
Temporary doctoral student years 3, and 4.

Please send your application, marked with reference number 6187/2011, to reach 
us by no later than February 29, 2012 to KI jobb and to Anna-Maria Bernstein, M 
54; Karolinska Institutet, 141 86 Stockholm, anna.maria.bernst...@ki.se. The 
following documents should be enclosed with your application in English or 
Swedish:
- Personal letter of introduction and CV
- Copy of degree certificate and grades

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