Hi, This hasn't been mentioned by the people who have answered so far so here we go: your molecular replacement solution and your SeMet solution to the phase problem are not necessarily using the same origin. There is a ccp4 program (is it phistats ? and there may be other programs around) that can deal with this.
Fred. > Message du 15/11/11 22:56 > De : "Feng Guo" > A : CCP4BB@JISCMAIL.AC.UK > Copie à : > Objet : [ccp4bb] Can I combine selenoMet data and MR model to solve the phase > problem? > > Hi, there, > > Maybe someone asked this question before, but I couldn't find it in the > archive. > > We use the native data to do molecular replacement before, but only part of > the model fit the density. After collect a new set of selenoMet data, we try > to use it to solve the phase, it solve some of the phase problem other than the MR, but still not complete. Is there anyway that I can somehow combine the two phases together? Thank you. > > Best, > > Feng >