Phenix does this (http://www.phenix-online.org/documentation/autosol.htm#anch125)

Phaser-EP (http://www.phaser.cimr.cam.ac.uk/index.php/Experimental_Phasing#Combined_MR_and_SAD_Phasing)

and SHELX using an experimental version you have to get from George Sheldrick.

Jon

--
Jonathan P. Schuermann, Ph. D.
Beamline Scientist
NE-CAT, Building 436E
Advanced Photon Source (APS)
Argonne National Laboratory
9700 South Cass Avenue
Argonne, IL 60439

email: schue...@anl.gov
Tel: (630) 252-0682
Fax: (630) 252-0687




On 11/15/2011 03:56 PM, Feng Guo wrote:
Hi, there,

Maybe someone asked this question before, but I couldn't find it in the archive.

  We use the native data to do molecular replacement before, but only part of 
the model fit the density. After collect  a new set of selenoMet data, we try 
to use it to solve the phase, it solve some of the phase problem other than the 
MR, but still not complete. Is there anyway that I can somehow combine the two 
phases together? Thank you.

Best,

Feng


--
Jonathan P. Schuermann, Ph. D.
Beamline Scientist
NE-CAT, Building 436E
Advanced Photon Source (APS)
Argonne National Laboratory
9700 South Cass Avenue
Argonne, IL 60439

email: schue...@anl.gov
Tel: (630) 252-0682
Fax: (630) 252-0687

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