Dear harvey Consider your purification and preparation protocols - is the sample pure and homogenous? Poul
On 21/02/2011, at 03.29, Harvey Rodriguez <h.rodriguez.x...@gmail.com> wrote: > Dear CCP4BBers, > > Recently I got a crystal which appeared in the condition 2.1M DL-Malic Acid, > pH 7.0. The crystal looks like a dumbbell but was composed of a cluster of > very thin needles as shown in the picture. The crystal can be repeated but > the diffraction is poor. I have tried the grid optimization by pH and salt > concentration gradients, however there was no improvement in either the shape > or the quality of the crystal. Does anyone have some experiences in > optimizing this kind of crystals? Any suggestion is appreciated! > > Harvey > <dumbbell crystals.jpg>
