Dear All, My SeMet protein crystals have a needle-like morphology, worse than that of the native xtals. Also, although the cell dimensions of both forms is very much similar, the SeMet xtals are twinned(as indicated by Ctruncate plots). I was wondering if such cases were commonly seen, also is it alright to microseed my SeMet protein drops with seeds from the native xtal. I would be grateful if someone could shed light on this.
thanks in advance, -- Amit Sharma, Postdoctoral Fellow, Department of Biophysics, Johns Hopkins University, Baltimore, MD21218
