On Wednesday 25 August 2010 03:19:53 pm zhan...@umbc.edu wrote:
> I mean the density of 2mFo-DFc or Fc maps.
I still don't understand. Real space refinement will minimize a fit
of model to density in whatever map you give it. It's up to you
which coefficients are used to calculate the map you are refining
against.
Ethan
>
> > On Wednesday 25 August 2010 03:13:53 pm Hailiang Zhang wrote:
> >> Hi Garib:
> >>
> >> Actually I tried coot real space refine zone, but the model seems not
> >> sliding into the best density map (I also tried dragging it around, but
> >> still not working fine). Then I found some comments saying minimizing
> >> the
> >> difference between 2mFo-DFc and Fc may be better, thats why I am asking
> >> for this.
> >
> > Wait a minute. If you are minimizing a residual based on differences
> > between Fo and Fc (never mind the precise coefficients), how is this
> > "real space refinement"?
> >
> > (puzzled) Ethan
> >
> >
> >>
> >> Best Regards, Hailiang
> >>
> >> > Why you do not use coot? It does exactly what you want.
> >> >
> >> > regards
> >> > Garib
> >> >
> >> > On 25 Aug 2010, at 22:33, Hailiang Zhang wrote:
> >> >
> >> >> Hi,
> >> >>
> >> >> Can some utilities of CCP4 do the real-space refinement locally
> >> >> with the
> >> >> residue range explicitly specified?
> >> >>
> >> >> By the way, I have registered phenix bb. Just didn't realize this
> >> >> before,
> >> >> sorry again.
> >> >>
> >> >> Best Regards, Hailiang
> >> >
> >> >
> >>
> >
> > --
> > Ethan A Merritt
> > Biomolecular Structure Center, K-428 Health Sciences Bldg
> > University of Washington, Seattle 98195-7742
> >
> >
>
>
>
--
Ethan A Merritt
Biomolecular Structure Center, K-428 Health Sciences Bldg
University of Washington, Seattle 98195-7742
