Kurt Krause's group solved a structure from hollow crystals:

J. Mol. Biol. 2002 Apr 26;318(2):503-18.
The crystal structure of Trichomonas vaginalis ferredoxin provides insight into 
metronidazole activation.
Crossnoe CR, Germanas JP, LeMagueres P, Mustata G, Krause KL.



________________________________
From: Andre Ambrosio <andre.ambro...@cebime.org.br>
Reply-To: Andre Ambrosio <andre.ambro...@cebime.org.br>
Date: Wed, 2 Jun 2010 14:07:14 -0500
To: <CCP4BB@JISCMAIL.AC.UK>
Conversation: [ccp4bb] Off-topic: hollow protein crystals
Subject: [ccp4bb] Off-topic: hollow protein crystals

Dear all,

We have recently obtained crystals from a small protein, and interestingly, at 
least for me, they are hollow trigonal rods (please see pictures attached).
Just out of curiosity, has anybody ever seen such feature for protein crystals 
before?

Regards,
-Andre.

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