Dear Rex, It might still be while before a structure of a full-length voltage-gated sodium channel (or voltage-gated calcium channel) comes along. Keep an eye on the NaChBac channel (originating from Bacillus species), as this prokaryotic sodium-selective channel will likely be the first to represent the sodium channel family. (Science.<http://www.ncbi.nlm.nih.gov/pubmed/11743207> 2001 ;294,2372-2375)
There are structures of small cytoplasmic loop segments (PDB ID 2KAV, 1BYY, 1QG9), but these won't tell you anything about sodium selectivity. cheers Filip Van Petegem On Wed, May 26, 2010 at 4:50 AM, Rex Palmer <rex.pal...@btinternet.com>wrote: > Does anyone know of the existence of a structure for a voltage gated Na > (not K) channel? > > Rex Palmer > Birkbeck College, London > -- Filip Van Petegem, PhD Assistant Professor The University of British Columbia Dept. of Biochemistry and Molecular Biology 2350 Health Sciences Mall - Rm 2.356 Vancouver, V6T 1Z3 phone: +1 604 827 4267 email: filip.vanpete...@gmail.com http://crg.ubc.ca/VanPetegem/
