(B355) Post-doctoral Training Fellow - Cancer Research UK Centre for Cancer Therapeutics

Section of Cancer Therapeutics (including the Cancer Research UK Centre for Cancer Therapeutics)

The Institute of Cancer Research (a college of the University of London) is a world-class cancer research organisation with HEFCE RAE ratings of international excellence across all of its research programmes, including cancer drug discovery and development. In partnership with The Royal Marsden NHS Foundation Trust, we form the largest comprehensive cancer centre in Europe, dedicated to research that extends from epidemiology, genetics and molecular biology, through drug discovery and development, to cancer diagnosis and patient treatment.

Cancer Therapeutics is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. Our exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible including medicinal chemistry, biology, drug metabolism and clinical specialists.

A Post-doctoral position is available immediately in Dr Rob van Montfort’s Hit Discovery and Structural Design Team within the Centre. The Post-doc will be involved in high-throughput X-ray crystallography and fragment-based screening and will be responsible for crystallisation and structural analysis of protein-ligand complexes from the Centre’s drug discovery programmes. The successful candidate will interact closely with the biology, computational chemistry and medicinal chemistry teams at the Centre as well as with the protein crystallographers in the Section of Structural Biology in which the crystallography efforts of Dr van Montfort’s team are embedded. Therefore the successful candidate will be expected to work across the two sites in Chelsea, London and Sutton, Surrey.

Applicants must have a PhD in a biological or physical science, and experience in macromolecular crystallography / crystallisation (to include protein biochemistry, protein crystallisation, & protein crystallography). Experience in molecular biology, protein purification, and/or structure-based drug design will be an advantage.

The starting salary for the position will be in the range £29,695 to £32,024 p.a. inclusive (based on previous post-doctoral experience) and the post is offered initially on a fixed term contract of up to 2 years. Informal enquiries to rob.vanmontf...@icr.ac.uk or isaac.westw...@icr.ac.uk Please DO NOT send your application to Dr van Montfort or Dr Westwood; CVs must be submitted in line with the instructions below.

For more details see our website: www.icr.ac.uk

To apply please email your CV and covering letter (addressing where you meet the person specification and incl. the names and addresses of two referees), to: recruitm...@icr.ac.uk, quoting job reference number B355.

In a separate email, please send your completed equal opportunities monitoring form quoting the job reference number above.

Closing date: Friday 5th March 2010



Dr. Rob van Montfort
Team Leader Hit Discovery and Structural Design
Sections of Cancer Therapeutics and Structural Biology
The Institute of Cancer Research
15 Cotswold Road
Sutton SM2 5NG
UK

Tel:
+44-(0)20-8722-4364 (Sutton)
+44-(0)20-7153-5142 (Chelsea)
Email: rob.vanmontf...@icr.ac.uk


The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company 
Limited by Guarantee, Registered in England under Company No. 534147 with its 
Registered Office at 123 Old Brompton Road, London SW7 3RP.

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