Hi, I have a question about the refinement by Refmac program in CCP4 package. I tried both the old version(1.4.4) and the latest version (2.0.5) for restrained refinement, and they gave me different result. For old version, it's 0.192/0.250--> 0.191/0.247, while for the latest version, R/Rfree=0.202/0.254- ->0.194/0.255. For both version, I use the weighting term of 0.05. I am wondering which version will be better? or I did something wrong? Thank you.
Feng
