informahealthcare.com/doi/pdf/10.1517/17460441.1.1.1
Quoting c.weinert <c.wein...@bioc.uzh.ch>:
Dear all.
I am looking for a library of small (biologically relevant)
compounds to test binding to a protein. Does somebody know, if there
is a company that sells such a library for fragment based library
screening? (to a reasonable price).
And does anybody has experience with screening such libraries? I
assume that one approach would be soaking the protein with the
compounds, followed by SEC and MS analysis. Anybody tried directly
soaking crystals followed by X-ray analysis?
Thanks alot already in advance for your help.
Sincerely,
Christopher
--
Shao-Yang Ku
EIPOD Post-doctoral fellow
Schneider Group
EMBL c/o DESY
Notkestr. 85
22603 Hamburg phone: 0049-(0)40-89902-160
Germany email: s...@embl-hamburg.de