informahealthcare.com/doi/pdf/10.1517/17460441.1.1.1

Quoting c.weinert <c.wein...@bioc.uzh.ch>:

Dear all.

I am looking for a library of small (biologically relevant) compounds to test binding to a protein. Does somebody know, if there is a company that sells such a library for fragment based library screening? (to a reasonable price).

And does anybody has experience with screening such libraries? I assume that one approach would be soaking the protein with the compounds, followed by SEC and MS analysis. Anybody tried directly soaking crystals followed by X-ray analysis?

Thanks alot already in advance for your help.

Sincerely,
Christopher




--
Shao-Yang Ku
EIPOD Post-doctoral fellow
Schneider Group
EMBL c/o DESY
Notkestr. 85
22603 Hamburg                    phone: 0049-(0)40-89902-160
Germany                          email: s...@embl-hamburg.de

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