Dear all.
I am looking for a library of small (biologically relevant) compounds to
test binding to a protein. Does somebody know, if there is a company
that sells such a library for fragment based library screening? (to a
reasonable price).
And does anybody has experience with screening such libraries? I assume
that one approach would be soaking the protein with the compounds,
followed by SEC and MS analysis. Anybody tried directly soaking crystals
followed by X-ray analysis?
Thanks alot already in advance for your help.
Sincerely,
Christopher
