maybe my message was a bit abrupt, what I meant was:
- if it (auto)builds using the real sequence and refines, you are sure to have found the right solution. At 2.0 Angstrom this should only take a few hours. - if it doesn't, you may still have the right solution, but perhaps you made a mistake in transferring the solution correctly to Arp-Warp or your other (auto)building program, you may have twinning, or some other small or major post-solution problem. On the other hand, you may not have the right solution, in which case you will have to back to MR (try different MR programs) or try another phase determination technique involving heavy atoms.
Mark

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