More information about the two ligand bound structures, each protein is composed of two globular domains, between the two globular domains, there lies a deep cleft and ligand sits or buried there comfortably. These two domains are connected by a hinge region, here we want to model how this hinge region moves upon ligand binding. Any recommendation for any program which can do this task well. Thanks ahead.
Donghui On Sun, Aug 9, 2009 at 8:37 PM, wu donghui <wdh0...@gmail.com> wrote: > Dear CCP4ers, > Recently we have solved two structures from E.coli in high resolution, > which have bound two different ligands tightly already. Here I want to know > if there is any program which can let us model the structure of our apo > proteins confidently. Thanks ahead for any comment and input. > > Regards, > > Donghui >
