Hi, 
 
May be you can use "modeller" to model the apo structure using the structure of 
complex as template.
 
May you success! 
 
  
 ------------------ Original ------------------ 
  From: "wu donghui"<wdh0...@gmail.com>;
 Date: 2009年8月9日(星期天) 晚上8:37
 To: "CCP4BB"<CCP4BB@JISCMAIL.AC.UK>; 
 Subject: [ccp4bb] How to model apo protein structure from solved ligand bound 
high resolution structure?

  
Dear CCP4ers, 

 Recently we have solved two structures from E.coli in high resolution, which 
have bound two different ligands tightly already. Here I want to know if there 
is any program which can let us model the structure of our apo proteins 
confidently. Thanks ahead for any comment and input.
 

 Regards,
 

 Donghui

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