All
It seems I have a case where I have 5595 reflections but my protein is
about 102 residues. With a mean atom / residue * 4 parameters for
each atom I get about 7833 parameters. So it seems that I have a
observation : parameter ratio < 1. There is only 1 molecular per asu
so there's no hope in using NCS. Phases to be obtained from a pretty
good MR solution. Does anyone have any suggestions/protocols/
references for refining with obs:parameter < 1 ?
thanks
FR
---------------------------------------------
Francis Reyes M.Sc.
215 UCB
University of Colorado at Boulder
gpg --keyserver pgp.mit.edu --recv-keys 67BA8D5D
8AE2 F2F4 90F7 9640 28BC 686F 78FD 6669 67BA 8D5D
