Actually sc is part of the ccp4 package.
(more $CDOC/sc.doc)
The reference describing the procedure is:
1. Michael C. Lawrence and Peter M. Colman J. Mol. Biol., 234, p946 -
p950 (1993)
As you say, it calculates shape complimentarity of the surfaces as they
are docked in the structure. So before you attribute changes in sc to
conformational changes, be sure the surfaces haven't moved wrt each other!
Cheers,
Ed
Oganesyan, Vaheh wrote:
Colleagues,
Would some one kindly suggest software that calculates shape
complementarity of two interacting proteins based on co-crystal
structure?
I've seen number of reports with "sc" parameter included but none of
those mention how it was done.
Among non-runnable programs in CCP4 there is the sc program that indeed
does not run.
Thanks in advance.
_______
Vaheh
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