*Postdoctoral Positions in Macromolecular Crystallography* are immediately available in the Lucy Malinina laboratory at the Structural Biology Department of CICbioGUNE (Bilbao, Spain). We use the X-ray crystallographic approaches to elucidate structural principles of a biological intermolecular recognition for developing the means to effectively use and pharmacologically modulate protein specificity of a diverse nature. We focus our efforts on human neurodegenerative diseases, and currently study complexes with RNA in Project_1 "Structural Basis for Suppression of Human Trinucleotide Repeat Expansion Diseases (TREDs)" and glycolipids in Project_2 "Molecular Basis for Manipulating the Selectivity of Glycolipid Transfer". Other projects are under development.
*The crystallographic platform* includes a Bruker Microstar-H rotating anode generator, MAR345-DTB image plate, Bruker-135 mm CCD detector system, Helios confocal optics, two Oxford Cryosystem Series 700, TECAN-EVO100 liquid handling robot, Mosquito nanodispenser, a Bruker Crystal Farm, and supporting computers/software. *The biochemical laboratory *is supported by all necessary equipment for protein expression/isolation/purification, and oligonucleotide synthesis/purification as well. *Key Qualifications:* - PhD in physics, chemistry, biochemistry, biophysics or related field - Experience working in the area of macromolecular crystallography, including o the X-ray data collection for biological crystallography, o the use of computer programs required for biological crystallography, o crystallization with use of robotics hardware and control systems. To apply please submit before December 20, 2008 a cover letter, CV, and three references addressed to [EMAIL PROTECTED] with ref. "postdoc application" in the subject line.
