Postdoctoral Research Assistant in Protein Crystallography Ref: 131

This is a final reminder for this post. The closing date is the 8th March 2008.

Applications are invited for a three year Postdoctoral position, funded by the MRC, in the laboratory of Dr. Darren Thompson. The successful candidate will work on the Complement component C1. The Complement system is part of the innate immune system and is implicated in such conditions as arthritis and heart disease. The aim of the project is to determine the structure of this complex and investigate its stability and activity. The work will involve the use of X-ray crystallography, E.M, fluorescence and DLS.

The school is well equipped for protein biophysics including: Circular dichroism (Jasco CD), and state of the art UV/Vis rapid scan and fluorescence /anisotropy /CD stopped-flow (Applied Photophysics * and SX18MV stopped flow) and equilibrium fluorescence. The Department of Biochemistry houses protein crystallography facilities (RU-H3RHB rotating anode X-ray generator with Osmic max-Flux optics and RAXIS-IV image plate area detector and MSC cryo system) facilities and additional biophysics facilities including ITC and atomic force microscopy. There are also state of the art facilities for microarrays and the newly-created Sussex Centre for Advanced Microscopy provides state of the art facilities for confocal, 2-photon, and CCD microscopy, with fluorescence correlation and lifetime capabilities, a Hitachi7100 transmission electron microscope and cryo- and scanning electron microscopy.

Applicants should have appropriate degrees and experience in protein biochemistry and protein crystallography. Salary will be within the range £24,403 - £27,466 per annum, depending on qualifications and experience. This post is available immediately and will be offered on a fixed term contract for a period of 3 years.

Please direct informal enquiries to Dr. Darren Thompson: [EMAIL PROTECTED]

Closing date for applications: 8th March 2008

For full details and how to apply see www.sussex.ac.uk/jobs

Application details are available from and should be returned to Human Resources, Sussex House, University of Sussex, Falmer, Brighton BN1 9RH. Tel: (01273) 678706, fax: (01273) 877401, Email: [EMAIL PROTECTED] Details of all posts can also be found via www.sussex.ac.uk/jobs

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