Hi all,

Jacob Keller wrote:


Does anyone know of a bioinformatics counterpart of ccp4? It seems like there should really be such an entity, so that folks would not have to write scripts, reinventing the wheel all of the time. I am trying right now to manipulate some sequences into various forms, and I was imagining a "moleman" homolog for bioinformatics (perhaps seqman....?).

There *was* a CCP for the bioinformatics community - CCP11, which started life in the 1980s (yes, before ever the term "bioinformatics" was coined) to support software for sequence analysis. It ran continuously until 2005, when its last grant was rejected, and funded software development, support and training, but it never managed to attract CCP4's level of industrial funding.

One of the last things the project supported was EMBOSS (mentioned by Claudine), which is still being developed; its home page is http://emboss.sourceforge.net/. It may well have some of the applications that you are looking for. There is a general mailing list [EMAIL PROTECTED] that has much lower traffic than this one.

I was involved in CCP11 for about the last five years of its existence. I and others are not yet convinced that its ecological niche has been fully occupied, and plans for a grant re-submission occasionally rumble on. I would be interested to hear of any others who think that bioinformatics, as a discipline, is missing the service provided so ably by CCP4.

Of course, one problem we have now that we didn't have in the 1980s, when specialist hardware was needed for a simple sequence comparison, is to define the boundaries of "bioinformatics". But that is another question, and this list is not the right place to ask it!

Cheers,

Dr. Clare Sansom
[EMAIL PROTECTED]
Senior Associate Lecturer, Birkbeck College, London, UK
Freelance bioinformatics consultant and science writer

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