*Summary*

The Structural Genomics Group at the DOE Joint Genome Institute (JGI) in Walnut Creek, CA has an exciting Research Scientist opportuntiy available in the area of x-ray crystallography. Will Study the assembly and the structural basis function of carboxysomes, related bacterial microcompartments and other proteins related to the Department of Energy's (DOE) bioenergy related missions using single crystal X-ray diffraction techniques with synchrotron radiation. Research will be conducted at the DOE Joint Genome Institute with access to the University of California, and the Lawrence Berkeley Laboratory and offers a rich and dynamic scholarly environment with the latest in genomics, bioinformatics and structural biology. Will report to the Structural Genomics Program Lead.

*Duties*

/Essential -/ Design and carry out experiments (from protein preparation to structure analysis) aimed at elucidating the structural basis of bacterial microcompartment function. Conduct X-ray crystallographic structure determination and structure analysis of component proteins of bacterial microcompartments. Coordinate structural analysis (x-ray crystallography and small angle x-ray scatteries) of proteins. Evaluate and implement appropriate tools for structural studies. Troubleshoot all stages of experimental process from protein preparation through structure analysis. Interface with collaborators, JGI staff, management, and sponsors at other national laboratories.

/Marginal -/ Attend and present technical status reports at group meetings. Keep an accurate and detailed laboratory notebook. May direct the work and/or supervise technical support staff, student assistants and postdocs as necessary. Assist with the preparation of funding proposals and research publications

*Qualifications*

/Essential -/ PhD in biochemistry, biophysics, or a closely related field. Experience in all phases of X-ray structure determination (including data processing, phase determination and improvement, model building, protein structure refinement and interpretation). Experience in overexpression and purification of protein. Demonstrated ability to conduct and perform collaborative research and effectively interact with a broad range of colleagues with tact and diplomacy. Demonstrated ability to independently carry out creative research within an established framework. Ability to organize and present reports to collaborators, JGI staff, management, and sponsors. Working Knowledge of bioinformatics tools. Effective interpersonal skills necessary for working in a diverse team environment. Ability to work independently and as a team member in a diverse team environment. Ability to interact with work groups and collaborators outside of the laboratory. Experience preparing funding proposals and research publications

*Notes*

This is a 2 year term appointment with the possibility of renewal dependent on performance, continuing availability of funds and ongoing operational needs. Work will be performed at the DOE Joint Genome Institute (JGI), Production Genomics Facility located in Walnut Creek, CA.

*To Apply:
Go to
http://jobs.lbl.gov/LBNLCareers/details.asp?jid=21059&p=1

/or to /The Joint Genome Institute Website, under /Employment/
*

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Cheryl A. Kerfeld Ph.D.
Education/Structural Genomics
DOE Joint Genome Institute
2800 Mitchell Drive
Walnut Creek, CA 94598//
Adjunct Associate Professor
Plant and Microbial Biology
University of California, Berkeley
(925) 296-5691
[EMAIL PROTECTED]

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