A senior scientist or postdoctoral fellow position will be available in August 2007 in the Brinen lab in the department of Cellular and Molecular Pharmacology at the University of California, San Francisco. The Brinen lab is part of the UCSF Tropical Disease Research Unit, the UCSF Macromolecular Structure Group, as well as the Sandler Center for Basic Research in Parasitic Diseases. State of the art resources are available for all aspects of X-ray crystallographic research, including ample synchrotron beam time at both the Advanced Light Source (ALS) and the Stanford Synchrotron Radiation Laboratory (SSRL). Active research project areas include structure/function of proteolytic enzymes key to the lifecycle of several parasitic organisms responsible for infectious disease; structure-guided drug design against targets in parasitic infection; the structure/function roles of proteases in allergic response, protein-protein interactions in human lung biology and a newly funded drug design project against kinases implicated in breast tumor development and progression. See http://cmp.ucsf.edu/faculty/pdb_show.html?id=brinen .
Requirements: Applicant must have a Ph.D. in chemistry, biology, biochemistry or a related field. Absolutely required are proven experience in all aspects of macromolecular crystallography. Protein purification experience is expected; molecular biology and enzymology experience preferred. Experience using synchrotron light sources is a plus. Written and spoken communication skills and the ability to work with an extended network of collaborators are a must. Hiring at either the postdoctoral level or more advanced professional scientist level will be considered. Interested parties should contact Linda Brinen at [EMAIL PROTECTED] and provide a detailed CV, names of three references and a brief statement of research interests. Applications will be reviewed starting May 15th. --- Linda S. Brinen, PhD Adjunct Assistant Professor Dept of Cellular & Molecular Pharmacology and The Sandler Center for Basic Research in Parasitic Diseases Phone: 415-514-3426 FAX: 415-502-8193 E-mail: [EMAIL PROTECTED] QB3/Byer's Hall 508C 1700 4th Street University of California San Francisco, CA 94158-2550 USPS: UCSF MC 2550 Byer's Hall Room 508 1700 4th Street San Francisco, CA 94158
