Thanks a lot for the replies. The option which allows to set the chirality restraints to "both" was exactly what i was looking for, since i use refmac for refinement. Surprisingly, the binding site seems not to be stereoselective in this case. greetings, david -- "Feel free" - 10 GB Mailbox, 100 FreeSMS/Monat ... Jetzt GMX TopMail testen: http://www.gmx.net/de/go/topmail
