Take a look at BiocSklearn. 

Nitesh

> On Feb 18, 2020, at 8:11 AM, Zhang, David <david.zhang...@ucl.ac.uk> wrote:
> 
> Dear all, 
> 
> I’m a bioinformatics PhD student at UCL who’s recently been trying to develop 
> an R package that has some python dependencies. Specifically, areas of my 
> current pipeline are written in python for speed and any ML has been 
> implemented through sklearn. I was wondering what you would advise as the 
> best practice of integrating python code into Bioconductor/R p
> packages? E.g. R to python interfaces (such as reticulate) or advising 
> package users to call python scripts independently or re-writing python code 
> in R? 
> 
> Any advice would be much appreciated. 
> 
> Many thanks in advance, 
> 
> David 
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