Hi,

I am currently finishing a package for submission to Bioconductor 3.1 and, therefore, I am trying to make everything work on the latest R-devel, but I have an issue with linking to Rsamtools. It seems that Rsamtools installs the libraries libbam, libbcf, and libtabix to the usrlib/x86_64/ directory in its package directory, but packages linking to Rsamtools seem to expect the libraries in usrlib/. Because of this problem, neither my package nor other packages relying on Rsamtools, e.g. VariantAnnotation, can be installed. The check results on http://bioconductor.org/checkResults/3.1/bioc-LATEST/ tell me that there is no such issue on the BioC build servers, but the R-devel used on these machines is much older than mine. Any clues?

I am using "R Under development (unstable) (2015-03-18 r68019)" on 64-bit Linux which I installed today. However, the problem already occured on last week's R-devel. The problem is really serious for me because I cannot test my package as long as it cannot link to Rsamtools. I want to emphasize that my package passes all checks without any errors or warnings on R 3.1.2 and Bioconductor 3.1. So I do not think I am doing anything wrong (and the developers of VariantAnnotation neither).

Any help is gratefully appreciated.

Thanks,
Ulrich

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