Gviz has a nice way of working with TxDb instances to derive gene models. It can be cumbersome to refer to a TxDb instance, and the Homo.sapiens OrganismDb instance is very convenient to work with.
I do not see any straightforward way to extract a reference to a TxDb from Homo.sapiens. I could traverse the graph slot but class?OrganismDb makes no reference to this. In summary, I think it would be good to document the OrganismDb API and to think about preferences for using OrganismDb as opposed to TxDb and OrgDb (org.Hs.eg.db) whenever possible. BTW I attempted to 'patch' Gviz by substituting OrganismDb for TxDb -- there are only two references to TxDb in Gviz ... and it would seem that the necessary operations apply to OrganismDb just as well as to TxDb. But the APIs are not in sync ... I ran into seqlevels0 ... and that is something of a mystery. [[alternative HTML version deleted]] _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel