Dear Bioconductor-community,
I would like to introduce a new package to you: PAA. PAA (Protein Array Analyzer) is a package for protein microarray data analysis (esp., ProtoArray data). PAA imports single color protein microarray data that has been saved in gpr file format. After pre-processing (background correction, batch filtering, normalization) univariate feature pre-selection is performed (e.g., using the "minimum M statistic" approach). Subsequently, a multivariate feature selection is conducted to discover biomarker candidates. Therefore, either a frequency-based backwards elimination aproach or ensemble feature selection can be used. PAA provides a complete toolbox of analysis tools including several different plots for results examination and evaluation. I would be very happy to obtain suggestions concerning improvements and any other feedback. Hence, I would be pleased if you would test PAA and tell people working with ProtoArrays (or other protein microarrays) about the package. PAA-Link: http://bioconductor.org/packages/devel/bioc/html/PAA.html <http://bioconductor.org/packages/devel/bioc/html/PAA.html%20> Have a lot of fun with BioC 3.0 and PAA!!! Best regards, Michael ------------------------------------------------- Dipl.-Bioinform. Michael Turewicz Medizinisches Proteom-Center Ruhr-Universit�t Bochum Zentrum f�r klinische Forschung (ZKF) Raum E.142 Universit�tsstr. 150 D-44801 Bochum Tel.: +49 234 32 29 275 Fax: +49 234 32 14554 E-Mail: <mailto:michael.turew...@rub.de> michael.turew...@rub.de <http://www.medizinisches-proteom-center.de/> www.medizinisches-proteom-center.de [[alternative HTML version deleted]]
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