> Are you asking if you can rewrite your code to work faster, or are you asking > if the BioC devs need to improve the code to be faster?
I was suggesting that maybe the c function for GRanges could be optimised. > Another would be manually splitting each GRanges objects into its components: > seqnames, IRanges, strand, and metadata. Then concatenate these components > and build one big GRanges object. This approach gives: user system elapsed 63.488 11.092 74.786 which by using c was previously: user system elapsed 935.770 23.657 961.952 Thanks for the tip. I now remember using this approach at some time in the past. _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel