Hello, For a not so large list of GRanges:
> length(blockRanges) [1] 4029 > class(blockRanges) [1] "list" Which don't have an unreasonable number of elements in them: > summary(sapply(blockRanges, length)) Min. 1st Qu. Median Mean 3rd Qu. Max. 1 961 20710 55210 77680 759600 Combining them takes 15 minutes: > system.time(allRanges <- do.call(c, blockRanges)) sessionInfo() user system elapsed 935.770 23.657 961.952 > head(blockRanges[[1]]) GRanges with 6 ranges and 1 metadata column: seqnames ranges strand | conservation <Rle> <IRanges> <Rle> | <numeric> [1] chr1 [10918, 10918] * | 0.064 [2] chr1 [10919, 10919] * | 0.056 [3] chr1 [10920, 10920] * | 0.064 [4] chr1 [10921, 10921] * | 0.056 [5] chr1 [10922, 10922] * | 0.064 [6] chr1 [10923, 10923] * | 0.064 --- seqlengths: chr1 NA Could this code be faster ? > sessionInfo() R version 2.15.2 (2012-10-26) Platform: x86_64-pc-linux-gnu (64-bit) other attached packages: [1] GenomicRanges_1.10.5 IRanges_1.16.4 BiocGenerics_0.4.0 -------------------------------------- Dario Strbenac PhD Student University of Sydney Camperdown NSW 2050 Australia _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel