It's not a recent problem see:
https://github.com/numpy/numpy/issues/3837
https://github.com/numpy/numpy/issues/8559

And see:
http://modwsgi.readthedocs.io/en/develop/user-guides/application-issues.html#multiple-python-sub-interpreters

You were just being lucky before. Note that you can supposedly fix this 
issue by forcing all WSGI applications to run in the same interpreter using 
WSGIApplicationGroup %{GLOBAL} in your config

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