It's not a recent problem see: https://github.com/numpy/numpy/issues/3837 https://github.com/numpy/numpy/issues/8559
And see: http://modwsgi.readthedocs.io/en/develop/user-guides/application-issues.html#multiple-python-sub-interpreters You were just being lucky before. Note that you can supposedly fix this issue by forcing all WSGI applications to run in the same interpreter using WSGIApplicationGroup %{GLOBAL} in your config -- Resources: - http://web2py.com - http://web2py.com/book (Documentation) - http://github.com/web2py/web2py (Source code) - https://code.google.com/p/web2py/issues/list (Report Issues) --- You received this message because you are subscribed to the Google Groups "web2py-users" group. To unsubscribe from this group and stop receiving emails from it, send an email to web2py+unsubscr...@googlegroups.com. For more options, visit https://groups.google.com/d/optout.