From: "R-Elists" <list...@abbacomm.net>
   Date: Wed, 14 Apr 2010 08:43:21 -0700
   
   having spent the better part of a two days searching as well as trying
   different configs and SA restarts

   we do not have a "hardware horsepower" resource starvation issue
   
   in reference to the error
   
   spamd[30339]: bayes: cannot open bayes databases
   /home/spamd/.spamassassin/bayes_* R/W: lock failed: Interrupted system call

I'd guess that you have a bayes expire running that is either taking
too long or not finishing and leaving lock files around.

Turn off bayes_auto_expire and use bayes_learn_to_journal.
Add a cron job to periodically sa-learn --sync (say hourly)
and another cron job to do sa-learn --force-expire (daily/weekly)
-jeff

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