I highly recommend using Postfix to prevent some of this from even getting
through to SpamAssassin to begin with. 
This was the most helpful page for me. I've modified things to suit my own
needs, of course. The results have been stellar. SpamAssassin barely does
any work now.

http://jimsun.linxnet.com/misc/postfix-anti-UCE.txt



spamsux wrote:
> 
> SA is working for the most part beyond expectations, the only problem I¹m
> having is filtering spoofed email address (i.e. valid_u...@ourdomain.com).
> I
> am able to filter out non-valid user addresses (i.e.
> spam...@ourdomain.com).
> I run SA-Update daily, have piped well over 500 of these messages through
> sa-learn, yet they still come through. I know this is a generic outline of
> the problem, but it¹s a start, if you need more info I can send it.
> 
> -Jeff
> 
> 
> 
> Server Specs:
> Mac OSX Server 10.5.7
> SA 3.2.1
> Perl 5.8.8
> Postfix 2.4.3
> Amavisd 2.5.1
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 

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