To clarify a bit regarding what exactly the regression is: This works in earlier Apache 2.4 versions:
AddHandler proxy:unix:/run/sockets/uwsgi-fcgi.sock|uwsgi:// .php But with 2.4.60 and newer, this results in an error message: AH10097: error parsing URL //: Invalid host/port If one then tries to add localhost as a "host", as has been a workaround for e.g. Sympa using fcgi, uwsgi gets confused as described in the issue reported in Github. It appears therefore that Apache 2.4 handles uwsgi:// and uwsgi://localhost differently in how parameters are passed, and that this causes the regression. -- Jan