Thanks for your time, Christian! Firewall/networking between them: None. :-\
They are running on the same (virtual) machine - it's an EC2 host running ubuntu. I am running 3 instances of AMQ on it (it's a dev/test/qa type of environment) - the AMQ endpoints are configured as localhost:61617, localhost:61618, and localhost:61619. It's so strange - it'll work perfectly for several days, then the error rate starts climbing. I monitor it with AWS Cloudwatch, and I see solid performance for some time (I'm not seeing a pattern yet), then it starts rejecting messages (not all, just some), and then it kind of snowballs until it's rejecting 50-60% of them and things go bad from there. :( If there's any other info I can provide to help track this down, just ask - I'm looking to figure this out and understand why it's failing. I'm guessing it's something I buggered up in my configuration. :-/ If it would help, I can gist one of them on github and share a link to that. Larry